Semen testis expressed protein 101 and spermatid-specific thioredoxin reductase 3 levels may be biomarkers in infertile male

Abstract Objectives We aimed to determine the differences between normozoospermic and oligozoospermic individuals according levels of spermatid-specific thioredoxin reductase 3 (SPTRXR3/STRX3/TXNDC8/TXNRD3) testis expressed protein 101 (TEX-101), evaluate correlations spermiogram data biochemical parameters. Methods The study was carried out at Andrology Laboratory Medicine Faculty Selcuk University. Two groups were designed: Group 1: Normozoospermia (n=40, sperm concentration ≥ 15 million/mL), 2: Oligozoospermia; < million/mL). Seminal plasma SPTRXR3 TEX-101 analyzed with ELISA method. Spermiogram analysis evaluated WHO 2010 Kruger criteria. Results significantly different in normozoospermia (2.12 ± 0.08 ng/mL) compared oligozoospermia (1.55 0.04 ng/mL). (6.98 0.46 higher than (3.07 0.35 Both correlated statistically most Conclusions High low may be a biomarker evaluation male infertility. relations parameters indicates that results present new clinical approach biology male.